Series Description: This 3- part series will provide expert insight on how to incorporate systemic treatments when managing adult patients with moderate to severe atopic dermatitis. Our panelists share their viewpoints on measuring disease severity, the roles of IgE testing, patch testing and biopsy when evaluating a patient with atopic disease. Additionally they highlight the changing landscape of therapeutic options and provide an efficacy and safety overview of the newest additions to our treatment toolbox including: two monoclonal antibodies, the JAK inhibitors as well as older therapeutics. This series will leave you feeling more confident about your utilization of systemic treatment options for your adult patients with moderate to severe atopic dermatitis.